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Currently a series of MEBO products are in the process of being introduced to the U.S. market. 

For example, MEBO Wound Ointment is now going through the US Food & Drug Administration (FDA) regulatory process to be registered as a botanical drug.  The product has undergone a series of preclinical safety and toxicological examinations in the US.  All of the studies are performed in accordance with the guidelines of the International Conference on Harmonization (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use, and with Good Laboratory Practice (GLP) regulations.  MEBO Wound Ointment has been topically tested in intact and abraded animal skins, and examined for phototoxicity, irritation, and sensitization effects in New Zealand white rabbits and Hartley-derived albino guinea pigs. The results of these studies have shown that MEBO Wound Ointment is not a dermal irritant, ocular irritant, contact sensitizer, photo-sensitizer, or photo-irritant to test animals. A single oral dose study in Albino rats shows that 5g per kilogram of body weight caused no mortality or observable changes in any of study animals. According to Federal Hazardous Substances Act Regulations, MEBO Wound Ointment is not orally toxic to rats. The results of 28-day repeated dose studies in Sprague Dawley rats and Hanford minipigs have shown that daily dermal applications of MEBO Wound Ointment for 28 days are well-tolerated. No local or systemic test article-related effects are noted at any dosage level tested. Genotoxicity studies have shown that MEBO Wound Ointment does not exhibit any mutagenicity in the bacterial reverse mutation tests and is to be negative for the induction of chromosome aberrations in the in vitro chromosome aberration assay.

For more information please contact:

MEBO International, Inc.
Email: inter@mebo.com
Tel: +86 10 58701593 
Fax: +86 10 58700418

 
   
Corporate Alliance
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