Surgical wounds account for the majority of the incident of wounds globally. Most surgically sutured wounds are acute wounds that heal without complication in an expected time frame. However, visible scarring normally results, which is particularly undesirable in cosmetic surgery.
When the wound is rather big and messy with an extensive loss of tissue (e.g., open wounds that cannot be sutured), a large tissue defect results, which has to be filled by granulation tissue. This produces an intense inflammatory response at the edges of the wound, and it will take a long period of time to grow granulation tissue, if possible. Thus, the major challenge in the treatment of surgical wounds with massive tissue loss is to facilitate granulation tissue growth while minimizing or preventing infection, development of gangrene and formation of hypertrophic or keloid scars.
MEBO¡¯s regeneration therapy and products have been used successfully to regenerate massive tissue after trauma (see Section III above) and surgery, including cosmetic surgery. Application of this approach to cosmetic surgery has achieved maximized aesthetic outcomes. Petrou I. ¡°Healing help: Studies demonstrate role of moist wound dressings in more aesthetic scar outcomes¡± Cosmetic Surgery Times July 1, 2008.
1. Regeneration of Skin at Skin Graft Donor Sites
2. Regeneration of Wound after Cosmetic Surgery to Minimize Scar Formation
3. Regeneration of Wound Caused by Parenteral Nutrition Fluid Extravasation Injury